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Cortexian
October 16th, 2009, 08:16 PM
http://folding.stanford.edu/


Our goal: to understand protein folding, misfolding, and related diseases

http://www.stanford.edu/group/pandegroup/images/FAHdownload.png (http://folding.stanford.edu/English/Download)


What is protein folding?
Proteins are biology's workhorses -- its "nanomachines." Before proteins can carry out these important functions, they assemble themselves, or "fold." The process of protein folding, while critical and fundamental to virtually all of biology, in many ways remains a mystery.


Protein folding is linked to disease, such as Alzheimer's, ALS, Huntington's, Parkinson's disease, and many Cancers
Moreover, when proteins do not fold correctly (i.e. "misfold"), there can be serious consequences, including many well known diseases (http://folding.stanford.edu/English/FAQ-Diseases), such as Alzheimer's, Mad Cow (BSE), CJD, ALS, Huntington's, Parkinson's disease, and many Cancers and cancer-related syndromes.


You can help scientists studying these diseases by simply running a piece of software.
Folding@home is a distributed computing project -- people from throughout the world download (http://folding.stanford.edu/English/Download) and run software to band together to make one of the largest supercomputers in the world. Every computer takes the project closer to our goals. Folding@home uses novel computational methods coupled to distributed computing, to simulate problems millions of times more challenging than previously achieved.

What have we done so far?
We have had several successes. You can read about them on our Science (http://folding.stanford.edu/English/Science) page, on our Awards (http://folding.stanford.edu/English/Awards) page, or go directly to our Results (http://folding.stanford.edu/English/Papers) page.


Want to learn more?
Click on the links on the left for downloads or more information. You can also download our Executive Summary (http://www.stanford.edu/group/pandegroup/folding/FoldingFAQ.pdf), which is a PDF suitable for distribution. One can also help by donating funds to the project (http://folding.stanford.edu/English/Donate), via Stanford University.Start folding if you've got a decent GPU or CPU, it only uses available system resources and it will free up any resources required for other applications when they request them. There's no downside except for a slight increase in power usage and heat output from your PC.

Varmint260
October 16th, 2009, 08:44 PM
Pick me, pick me, I fold!

I don't have the application on my PC, but the PS3 comes with the application in order to put the cell processor to good use when I'm not using it. Though, I'm sure it sucks a fair chunk of electricity while it's running to be honest.

Cortexian
October 16th, 2009, 09:03 PM
Yea, I just got all my local computers setup and folding, warmed up the basement by a degree or two lol...

http://freelancer.modacity.net/pics/foldingstuff.jpg

Pyong Kawaguchi
October 16th, 2009, 09:18 PM
I am currently running this now, btw, I don't have a second internet connectiond own here, but could I have the ps3 do work, and upload it when it goes online?

Donut
October 16th, 2009, 09:22 PM
so this is an application that basically allows whoever is distributing it to whore you pc's unused resources to perform computations?

Cortexian
October 16th, 2009, 09:33 PM
so this is an application that basically allows whoever is distributing it to whore you pc's unused resources to perform computations?
Yes, to cure certain diseases.


I am currently running this now, btw, I don't have a second internet connectiond own here, but could I have the ps3 do work, and upload it when it goes online?
You don't need separate internet connections for each setup, you can use your router to split the connections like normal. I have all three of my computers running on the same network, makes it easy to monitor the folding. I'm not sure how the PS3 app works, but the Windows version has an option to "ask" for internet access in case you're not connected 24/7.

Pyong Kawaguchi
October 16th, 2009, 09:46 PM
No, I mean, I have a router, but I only have 4 ports on the router, and one wire down here, I want to be able to run both at the same time.

InnerGoat
October 16th, 2009, 09:54 PM
I ran F@H for a while when the GPU client for nvidia cards came out, stopped when I found out the completed work units were not usable in those early build or so... :-3

@pyong - get another router

Varmint260
October 16th, 2009, 10:21 PM
No, I mean, I have a router, but I only have 4 ports on the router, and one wire down here, I want to be able to run both at the same time.

I spent 30 bucks at my local The Source and got a five-port D-Link ethernet switch. I took my long internet cable that comes from the router upstairs, plugged it into the ethernet switch, then used two shorter cables from the switch to my PS3 and computer and it works just fine.

I have this one:
http://images.dlink.com/new/products/DSS-5PLUS/DSS-5PLUS_right.png

EDIT: Sorry, five-port, not four-port. Same thing anyhow.

Cortexian
October 16th, 2009, 11:04 PM
Yea Pyong, if you've got one cable from a router, just get a three port (minimum, one in / two out) switch and you'll be good to go. I recommend getting one that's the same brand as your router if you can.

Edit - Got a screencap at 22k PPD:
http://freelancer.modacity.net/pics/foldingstuff2.jpg

Kalub
October 17th, 2009, 02:39 PM
I spent 30 bucks at my local The Source and got a five-port D-Link ethernet switch. I took my long internet cable that comes from the router upstairs, plugged it into the ethernet switch, then used two shorter cables from the switch to my PS3 and computer and it works just fine.

I have this one:
http://images.dlink.com/new/products/DSS-5PLUS/DSS-5PLUS_right.png

EDIT: Sorry, five-port, not four-port. Same thing anyhow.



Piece of shit router tbqh dont get one of those

Varmint260
October 17th, 2009, 03:09 PM
Piece of shit router tbqh dont get one of those

Please read the post: it isn't a router.

Now, to be quite honest, yes, my switch is connected to another D-Link router and then a LinkSys modem. I haven't had any problems, however, so could you at least use some facts to back up that claim?

EDIT: I guess I should get back to the Folding@Home topic. Haven't folded in a little while; I'll start it up now.

Bhamid
October 18th, 2009, 07:08 AM
http://www.worldcommunitygrid.org/

This is like folding but it does other things like curing AIDS, Cancer etc

I think you can get the instructions to fold on that client if you download it but I've never tried.

Cortexian
October 18th, 2009, 04:58 PM
Folding is using all the resources I can give it right now, so I'm not even going to bother looking into that. Folding helps research on the following:
- Alzheimer's Disease (AD) (http://folding.stanford.edu/English/FAQ-Diseases#ntoc6)
- Huntington's Disease (HD) (http://folding.stanford.edu/English/FAQ-Diseases#ntoc7)
- Cancer and P53 (http://folding.stanford.edu/English/FAQ-Diseases#ntoc8)
- Osteogensis imperfecta (http://folding.stanford.edu/English/FAQ-Diseases#ntoc9)
- Parkinson's Disease (PD) (http://folding.stanford.edu/English/FAQ-Diseases#ntoc10)

And it helps improve research into antibiotics.

Cortexian
October 19th, 2009, 09:56 PM
People should donate to me so I can purchase a dedicated folding machine (http://secure.newegg.ca/WishList/PublicWishDetail.aspx?WishListNumber=15577148), we can make it the Modacity.net folding machine!

Edit - Holy shit do want:
http://atlasfolding.com/wp-content/gallery/buildtarget/atlasfolder-3-14-09-leftside_0.png
(That's 17 9800 GX2 dual core graphics cards (34 instances of FOlding@Home) folding 24/7.

Varmint260
October 20th, 2009, 01:31 AM
Edit - Holy shit do want:

[PICTURE]

(That's 17 9800 GX2 dual core graphics cards (34 instances of FOlding@Home) folding 24/7.

I bet it makes a wonderful space heater, too!

Cortexian
October 20th, 2009, 02:10 AM
I could do with a space heater in my igloo's basement!