I do. My left eye is 20/20 and my right eye is 20/200. After glasses, left eye is the same but right eye is 20/40. Can't get it any better. It's a problem with the nerve, not the eye.
My glasses work fine with the 3D glasses over top, though if your prescription can't compensate you to 20/20 in each eye I suppose the 3D effect wouldn't work.
It's impossible for me to ever get 20/20 vision (49/16, lazy eye as a kid, fucked my eye muscles up.), but I can still watch Imax 3d movies with my glasses on below.
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